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Updated: Jun 27, 2026

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System

Published on: September 20, 2018

[Perianal Paget's disease: five cases report].

A Minicozzi¹, F Leopardi, C Segattini

¹Divisione Clinicizzata di Chirurgia Generale, Ospedale Civile Maggiore, U niversitá degli Studi di Verona.

Il Giornale Di Chirurgia

|December 11, 2008

Summary

Extramammary Paget's disease (EMPD) of the perianal region is rare and often linked to other cancers. Surgical excision with reconstruction showed good outcomes, though local recurrence is possible, necessitating long-term monitoring.

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Last Updated: Jun 27, 2026

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System

Published on: September 20, 2018

Area of Science:

Oncology
Dermatology
Surgical Pathology

Background:

Extramammary Paget's disease (EMPD) is a rare neoplasm.
It is frequently associated with underlying cutaneous or visceral malignancies.
Perianal EMPD presents unique diagnostic and management challenges.

Observation:

This retrospective study analyzed 5 cases of perianal EMPD treated between 1996 and 2006.
Treatments included wide perianal excision, reconstruction with cutaneous grafts, and transanal resection for rectal adenocarcinoma.
Temporary sigmoid stomas were used in two cases to aid wound healing.

Findings:

No immediate or long-term complications were recorded.
Two patients experienced local recurrence; none developed distant metastases.
Four patients remain disease-free, while one with multiple recurrences died from unrelated heart failure.

Implications:

Perianal EMPD management requires a multidisciplinary approach.
The association with other malignancies necessitates thorough investigation and long-term follow-up.
Despite radical surgery, the potential for recurrence and metastasis highlights the complexity of this disease.