Related Experiment Video
Updated: Jun 27, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
[Staging of sleep based on electroencephalograms and mental electromyograms recorded by a simplified polygraph,
Noriko Ohisa1, Hiromasa Ogawa, Nobuki Murayama
1Department of Clinical Laboratory, Tohoku University Hospital, Sendai 980-8574, Japan. bigkyu-thk@umin.ac.jp
Objective:
To examine the feasibility of MemCalc-Malkin2, a simplified polygraph, for staging of sleep.
Design:
Electroencephalograms and mentalelectromyograms were recorded in 33 patients with possible obstructive sleep apnea-hypopnea syndrome by a simplified polygraph, MemCalc-Malkin2, and their frequencies were analyzed according to the sleep stage that were determined by a simultaneous conventional polysomnography.
Results:
Sleep was divided into four stages, i.e., awake(SWake), rapid eye movement phase(SREM), shallow non-REM sleep {S(1+2)}, and deep non-REM sleep {S(3+4)}. The ratio of the amount of beta waves to that of delta waves was significantly different between the four sleep stages (p < 0.05), being highest in SWake and lowest in S(3+4). Mental electromyographic discharges were significantly more active in SWake and S(1+2) than in S(3+4) and SREM.
Conclusion:
A MemCalc-Malkin2 appears promising for staging of sleep.

