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Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction
Published on: November 6, 2019
[Dermatomycosis--classification, etiology, pathogenesis, and treatment]
1Department of Dermatology, Teikyo University School of Medicine.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 17, 2008
Summary
Dermatomycoses, common skin fungal infections, are primarily caused by dermatophytes in Japan. Topical treatments are effective for these superficial epidermal infections.
Area of Science:
- Dermatology
- Mycology
- Epidemiology
Context:
- Dermatomycoses represent a significant portion of cases in dermatological clinics.
- Understanding the prevalence and distribution of fungal skin infections is crucial for public health.
- Epidemiological data guides clinical practice and resource allocation.
Purpose:
- To present the epidemiological findings of cutaneous fungal infections in Japan.
- To identify the most prevalent types of dermatomycoses and their causative agents.
- To inform therapeutic strategies based on epidemiological data.
Summary:
- Dermatophytosis is the most common fungal skin infection in Japan (89.1%), followed by candidiasis (8.4%) and Malassezia infections (2.4%).
- Tinea pedis is the most frequent dermatophytosis, with Trichophyton rubrum being the most isolated dermatophyte.
- Intertrigo is the most common clinical form of cutaneous candidiasis.
Impact:
- This study highlights the epidemiological landscape of dermatomycoses in Japan.
- Findings support topical application as the primary treatment for most dermatomycoses due to their location in the epidermis.
- Establishes a baseline for future research and intervention strategies in fungal skin infections.
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