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[Trichosporonosis]
1Department of Internal Medicine 2, Faculty of Medicine, Oita University.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 17, 2008
Summary
Trichosporonosis, a fungal infection, can be severe in immunocompromised individuals, especially those with diabetes. This review highlights the risks and clinical considerations for diabetic patients with this rare but potentially lethal mycosis.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Immunocompromised Host Infections
Context:
- Trichosporonosis presents a spectrum of clinical manifestations, from superficial to deep-seated mycosis.
- Deep-seated trichosporonosis is a lethal opportunistic infection primarily affecting immunocompromised patients, particularly those with neutropenia.
- Trichosporon asahii is a significant cause of non-Candida fungemia and disseminated infections in Japan.
Purpose:
- To review the existing literature on trichosporonosis in patients with diabetes mellitus.
- To emphasize the increased susceptibility of diabetic patients to trichosporonosis due to impaired leukocyte function.
- To alert clinicians to the potential for severe and lethal outcomes in immunocompromised hosts, including diabetics.
Summary:
- Trichosporonosis is a rare fungal infection with diverse clinical presentations.
- Diabetic patients exhibit a predisposition to trichosporonosis owing to compromised leukocyte function.
- The review focuses on the intersection of diabetes mellitus and trichosporonosis, underscoring clinical vigilance.
Impact:
- Highlights the clinical significance of trichosporonosis in a vulnerable patient population.
- Underscores the need for heightened awareness and careful management of trichosporonosis in diabetic individuals.
- Contributes to understanding opportunistic fungal infections in non-neutropenic immunocompromised hosts.
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