[Beta2-glycoprotein I polymorphism].

Hiromi Terashi1, Shiori Hashimoto, Shinichiro Uchiyama

  • 1Department of Neurology, Tokyo Wemens University, School of Medicine, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.

Summary

Antiphospholipid syndrome (APS) increases ischemic stroke risk in young adults. A specific beta2-GPI genetic variant (V247) is linked to cerebral infarction, potentially via platelet activation.

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