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Updated: Jun 27, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Antibacterial effect of N-Naphtylen Diamine Platinum (II) Choloride as novel compound
Abdolkarim H Chehregani1, Seyed Javad Sabounchi, Vida Jodaian
1Department of Biology, Faculty of Science, Cell and Molecular Lab, Bu-Ali Sina University, Hamedan, Iran.
Abstract:
The present study synthesized N-Naphtylen Diamine Platinum (II) Chloride (NDPC) as a novel compound and tested ability of it regarding inhibition of cell division in some bacteria. Present results indicate that NDPC could act as antimitotic compound. It was inhibited growth of some microorganism as experimental organisms. The most antimitotic effect was seen in pseudomonas aeurginosa that treated by 15 mg mL(-1). Application of NDPC in all concentrations also was inhibited division and growth of other bacterial cells. Although Escherichia coli is less sensitive to NDPC than others, but also inhibition of growth is significant in E. coli.
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