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Updated: Jun 27, 2026

Evaluating the Role of Mitochondrial Function in Cancer-related Fatigue
Published on: May 17, 2018
Reliance on God's help, depression and fatigue in female cancer patients
Arndt Büssing1, Julia Fischer, Thomas Ostermann
1University Witten/Herdecke, Germany. arndt.buessing@uni-wh.de
Objective:
Because an increasing number of studies indicate that a religious attitude is associated with lower depression, we intended to investigate the interrelationship between intrinsic religiosity and depressive behavioral symptoms in cancer patients with long-term courses.
Method:
In 396 female cancer patients recruited in East-Germany, intrinsic religiosity was measured with the scale Reliance on God's Help (RGH) from the AKU questionnaire; anxiety and depression with the Hospital Anxiety and Depression Scale; fatigue with the cancer fatigue scale (CFS-D); physical and mental health with the SF-12; adaptive coping styles and ESCAPE from illness with the AKU; and life satisfaction with a modification of Huebner's Brief Multidimensional Students' Life Satisfaction Scale.
Results:
Moderate depression-associated fatigue was prevalent in cancer patients with long term-cancer courses, while depression and anxiety were of minor prevalence. RGH, which was valued by several patients, correlated with Reappraisal: Illness as Chance; with life satisfaction dimensions such as future perspectives, overall life, and financial situation; to a small extend with Escape from Illness; and negatively with mental health. No significant correlations were found with respect to depression, anxiety, or fatigue.
Conclusions:
In contrast to cancer patients in final stages, cancer patients with long-term courses had just a moderate reliance on external divine powers. The addressed depressive behavioral symptoms were connected with internal adaptive coping styles such as Conscious Living/Positive Attitudes rather than intrinsic religiosity in response to disease.
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