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Updated: Jun 27, 2026

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Published on: December 27, 2024

[Persistent diarrhoea, hypotension, polyneuropathy].

R Sýkora¹, J Radej, I Novák

¹I Interní Klinika Lékarské Fakulty UK a FN Plzen.

Vnitrni Lekarstvi

|December 17, 2008

Summary

This summary is machine-generated.

This case report highlights systemic AA amyloidosis, a rare condition causing diarrhea, weight loss, and organ failure. Early suspicion of amyloidosis is crucial for patients presenting with this specific triad of symptoms.

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Last Updated: Jun 27, 2026

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Published on: December 27, 2024

Area of Science:

Nephrology
Gastroenterology
Neurology
Pathology

Background:

A 59-year-old male with hypertension and melanoma history presented with severe gastrointestinal and neurological symptoms.
The patient exhibited diarrhea, weight loss, circulatory collapse, hypotension, polyneuropathy, and worsening renal insufficiency.
Initial investigations for neoplasms, endocrine, autoimmune, infectious, or neurodegenerative disorders were inconclusive.

Observation:

A 59-year-old male with hypertension and melanoma history presented with diarrhea, weight loss, and circulatory collapse.
He also experienced symptomatic hypotension, polyneuropathy, and worsening renal insufficiency.
Extensive investigations ruled out common causes like neoplasms, endocrine, autoimmune, infectious, or neurodegenerative disorders.

Findings:

Kidney biopsy revealed AA amyloidosis, despite negative colon biopsies and absence of chronic inflammation or malignancy.
The patient ultimately succumbed to multiple organ failure.

Implications:

The triad of diarrhea, polyneuropathy, and hypotension should prompt suspicion for amyloidosis.
This case underscores the importance of considering rare diagnoses in complex clinical presentations.
Timely recognition of AA amyloidosis can potentially guide earlier therapeutic interventions.