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Updated: Jun 27, 2026

NiO Nanoflowers for Non-Enzymatic Amperometric Detection of Glucose
Published on: December 30, 2025
Voltammetric determination of glucose based on reduction of copper(II)-glucose complex at lanthanum hydroxide
Li Liu1, Jun-feng Song, Peng-fei Yu
1Institute of Analytical Science, Northwest University, Xi'an 710069, China.
Abstract:
A novel voltammetric method for the determination of beta-d-glucose (GO) is proposed based on the reduction of Cu(II) ion in Cu(II)(NH(3))(4)(2+)-GO complex at lanthanum(III) hydroxide nanowires (LNWs) modified carbon paste electrode (LNWs/CPE). In 0.1mol L(-1) NH(3).H(2)O-NH(4)Cl (pH 9.8) buffer containing 5.0x10(-5)mol L(-1) Cu(II) ion, the sensitive reduction peak of Cu(II)(NH(3))(4)(2+)-GO complex was observed at -0.17V (versus, SCE), which was mainly ascribed to both the increase of efficient electrode surface and the selective coordination of La(III) in LNW to GO. The increment of peak current obtained by deducting the reduction peak current of the Cu(II) ion from that of the Cu(II)(NH(3))(4)(2+)-GO complex was rectilinear with GO concentration in the range of 8.0x10(-7) to 2.0x10(-5)mol L(-1), with a detection limit of 3.5x10(-7)molL(-1). A 500-fold of sucrose and amylam, 100-fold of ascorbic acid, 120-fold of uric acid as well as gluconic acid did not interfere with 1.0x10(-5)mol L(-1) GO determination.
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