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Updated: Jun 27, 2026

Fabricating Cotton Analytical Devices
Published on: August 30, 2016
Development of a novel colorimetric indicator pad for detecting aldehydes
Evanly Vo1, David K Murray, Tricia L Scott
1Department of Health and Human Services, CDC/National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, 626 Cochrans Mill Road, Pittsburgh, PA 15236, USA. Eav8@cdc.gov
Abstract:
A colorimetric indicator was developed and a colorimetric indicator pad was fabricated for the rapid detection of aldehydes. The detection pad has two sides: an observation side on top and a barrier on the bottom. The top side contains a reagent which reacts directly with aldehydes to produce a color change, while the bottom side is coated with a double-sided plastic tape barrier to prevent the escape of chemicals. Sensitivity of the indicator pads was determined using the vapor sensitive ASTM F739 technique with the presence of the indicator. A significant indicator color change (yellow to red) occurred about 5 min before the infrared analyzer response of the ASTM method. The chemical principle and reaction characterization of the test are described. The stability and potential interferences of the indicator pad were also examined by directly spiking aldehydes and compounds with other functional groups, respectively, onto the indicator pads. The newly developed aldehyde indicator pad should find utility in detecting aldehydes in both liquid and vapor phases and in collecting aldehyde permeation through PPE for further study.
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