Related Experiment Video
Updated: Jun 27, 2026

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates
Published on: May 30, 2025
Cue reactivity in young marijuana smokers: a preliminary investigation
Kevin M Gray1, Steven D LaRowe, Himanshu P Upadhyaya
1Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425, USA. graykm@musc.edu
Abstract:
To develop and evaluate the feasibility of a cue reactivity paradigm for young marijuana smokers, the authors set up a laboratory procedure involving neutral and marijuana-related imagery, video, and in vivo cues. Fifteen adolescents and young adults with cannabis use disorders completed the procedure, which included continuous measurement of skin conductance and heart rate. Participants also completed questionnaires regarding marijuana craving before, during, and after cue presentations. Higher levels of craving and skin conductance were observed during marijuana cue presentations. The procedure appears to elicit cue reactivity among adolescents and young adults with cannabis use disorders and should be further evaluated and refined with a larger sample. Implications for future studies are discussed.

