Related Experiment Video
Updated: Jun 27, 2026

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
Published on: October 14, 2025
Current and future therapies for inflammatory bowel disease
Timothy L Zisman1, Sunanda V Kane
1Clinical Research Fellow in Gastroenterology, The University of Chicago Hospitals, 5841 S. Maryland Avenue MC 4076, Chicago, IL 60637, USA. timothy.zisman@uchospitals.edu
Biologic agents are revolutionizing inflammatory bowel disease treatment, offering remission for patients resistant to traditional therapies. Future strategies involve integrating these advanced treatments into clinical practice for ulcerative colitis and Crohn
Area of Science:
- Gastroenterology and immunology.
- Inflammatory bowel disease (IBD) research.
Background:
- Biologic agents have transformed IBD management.
- Achieving remission in refractory patients is now possible.
Purpose of the Study:
- To review the impact of biologic agents in IBD.
- To explore future therapeutic strategies for ulcerative colitis and Crohn's disease.
Main Methods:
- Literature review of biologic therapies in IBD.
- Analysis of current understanding of inflammatory pathways.
Main Results:
- Biologics offer significant remission rates in non-responsive IBD patients.
- Ongoing research identifies novel therapeutic targets.
Conclusions:
- Biologic agents are crucial in modern IBD treatment.
- Optimizing the integration of biologics into treatment algorithms is essential for future patient care.
More Related Videos
08:58Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
Published on: January 5, 2017
06:57Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells
Published on: September 18, 2016
Related Concept Videos
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Drugs for Treatment of Ulcerative Colitis in IBD
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids