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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

Prevention of preterm birth

Jeffrey M Denney1, Jennifer F Culhane, Robert L Goldenberg

  • 1University of Utah, Department of Obstetrics & Gynecology, Department of Maternal-Fetal Medicine, Salt Lake City, UT, USA. jeffrey.denny@hsc.utah.edu

Women'S Health (London, England)
|December 17, 2008
PubMed

Insights

Preterm birth rates are rising, driven by indicated and multiple births. More research is needed to identify which pregnant women benefit most from interventions to reduce spontaneous preterm birth.

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Perinatal Medicine

Background:

  • The US preterm birth rate approaches 13%, with increases linked to indicated preterm births and multiple births from assisted conception.
  • Few interventions effectively prevent spontaneous preterm birth or mitigate risks for indicated preterm birth.

Purpose of the Study:

  • To review current strategies for managing preterm birth.
  • To identify the need for better patient stratification for interventions.

Main Methods:

  • Literature review of obstetrical interventions and perinatal care strategies.
  • Analysis of factors contributing to preterm birth rates.

Main Results:

  • Corticosteroids for fetal maturation and regionalized perinatal care improve outcomes for preterm infants.
  • Progesterone and cerclage show promise in reducing spontaneous preterm births.

Conclusions:

  • While interventions improve outcomes for preterm infants, a critical need exists to define specific maternal populations who will benefit from preventative strategies.
  • Further research is essential to optimize the application of existing and emerging interventions for preterm birth reduction.

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