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Reversible computerized tomographic lesion following childhood seizures
H P Sachdev1, V K Shiv, S K Bhargava
1Department of Pediatrics, Maulana Azad Medical College, New Delhi, India.
Journal of Tropical Pediatrics
|June 1, 1991
Summary
Reversible computerized tomographic (CT) lesions can occur in children after seizures. These focal abnormalities, often seen in the parietal lobe, typically resolve with anti-epileptic drug treatment.
Area of Science:
- Pediatric Neurology
- Neuroradiology
- Epileptology
Background:
- Reversible computerized tomographic (CT) lesions post-seizures are increasingly reported, primarily in adults.
- Focal CT abnormalities following seizures in pediatric populations are less characterized.
Purpose of the Study:
- To document and characterize reversible focal CT lesions in children experiencing seizures.
- To evaluate the resolution patterns of these lesions with standard treatment.
Main Methods:
- Retrospective analysis of CT scans from 20 pediatric patients presenting with seizures.
- Detailed recording of lesion location, size, and characteristics on plain and enhanced scans.
- Assessment of lesion resolution on follow-up CT scans after anti-epileptic drug (AED) treatment.
Main Results:
- Focal CT lesions were identified in 20 children, predominantly in the parietal lobe (17 cases).
- Cerebral edema was present in 16 patients; enhanced scans revealed ring lesions (12) and hyperdense foci (5).
- All 20 children received AEDs, with complete resolution in 12 and significant resolution in 8 on repeat CT scans.
Conclusions:
- Reversible, CT-demonstrable focal abnormalities are a recognized occurrence in children following seizures.
- These findings highlight the potential for transient structural changes on neuroimaging in pediatric epilepsy.