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Updated: Jun 27, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Effect of maternal depression and anxiety on use of health services for infants
Laura N Anderson1, M Karen Campbell, Orlando daSilva
1University of Toronto, ON, Canada.
Objective:
To evaluate the association between postpartum maternal depressive symptoms or maternal anxiety and health services utilization (HSU) for infants.
Design:
Telephone survey.
Setting:
London-Middlesex region of Ontario.
Participants:
Mothers of infants 2 to 12 months of age between 2004 and 2005 (N = 655). This sample was drawn from a larger longitudinal cohort of mothers recruited during pregnancy.
Main Outcome Measures:
Maternal depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale. Anxiety was measured using the State-Trait Anxiety Inventory. Infant HSU outcomes included number of primary care provider (PCP) visits for infants < 6 months of age, number of PCP visits for infants 6 to 12 months of age, emergency department (ED) use, and walk-in clinic (WIC) use.
Results:
Multivariable regression methods were used to compare HSU for infants. After adjustment for confounders, no significant associations were observed between postpartum maternal depressive symptoms and PCP visits, ED use, or WIC use. Similarly, no significant associations were observed for maternal anxiety and PCP visits, ED use, or WIC use.
Conclusion:
In contrast to some previous studies, this study found no association between postpartum maternal depressive symptoms or anxiety and HSU for infants.
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