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Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

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Bilateral persistent hyperplastic primary vitreous.

¹Department of Radiology, Getwell Polyclinic and Hospital, Jaipur - 302 004, India. drtjain@yahoo.com

Indian Journal of Ophthalmology

|December 17, 2008

Summary

This summary is machine-generated.

Bilateral persistent hyperplastic primary vitreous (PHPV) is a rare condition presenting as leukokoria in infants. Imaging findings can help differentiate bilateral PHPV from retinoblastoma, aiding diagnosis.

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Area of Science:

Ophthalmology
Pediatric Imaging
Medical Diagnostics

Background:

Persistent hyperplastic primary vitreous (PHPV) is a congenital developmental anomaly of the eye.
While typically unilateral and sporadic, bilateral PHPV presents a diagnostic challenge, often mimicking retinoblastoma.
Leukokoria, or a white pupillary reflex, is a key clinical sign necessitating prompt investigation.

Observation:

A 3-month-old male infant presented with bilateral leukokoria.
Imaging was performed due to clinical suspicion of retinoblastoma.
Gray-scale ultrasound revealed echogenic bands from the lens to the optic disc in both eyes.

Findings:

Doppler examination confirmed arterial flow within the echogenic bands in both globes.
Computed tomography confirmed associated echogenic hemorrhage.
The imaging features were consistent with bilateral PHPV, distinguishing it from retinoblastoma.

Implications:

This case highlights the importance of considering bilateral PHPV in the differential diagnosis of bilateral leukokoria.
Advanced imaging techniques, including ultrasound and CT, are crucial for accurate diagnosis.
Early and correct diagnosis of bilateral PHPV is essential for appropriate management and to avoid unnecessary treatment for retinoblastoma.