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Published on: December 3, 2017
Concurrent development of spontaneous pyomyositis due to Staphylococcus epidermidis and Kikuchi-Fujimoto disease
Georgios Kalambokis1, Georgios Economou, Spiros Nikas
1The 1st Division of Internal Medicine, University Hospital, Ioannina, Greece.
Abstract:
Staphylococcus epidermidis is a common cause of infections associated with prosthetic devices and immunocompromised patients. Spontaneous pyomyositis due to the above pathogen is very uncommon. Kikuchi-Fujimoto disease (KFD) is a subacute necrotizing lymphadenitis, first described in Japan. A T cell-mediated hyperimmune response to various pathogens in a genetically susceptible individual has been primarily been considered in its pathogenesis. We report a patient who developed spontaneous pyomyositis caused by S. epidermidis concurrently with KFD, and discuss the possibility of S. epidermidis infection being the stimulant of KFD.
Insights
A rare case of spontaneous pyomyositis caused by Staphylococcus epidermidis occurred alongside Kikuchi-Fujimoto disease (KFD). This suggests Staphylococcus epidermidis may trigger KFD in susceptible individuals.
Area of Science:
- Infectious Diseases
- Immunology
- Pathology
Background:
- Staphylococcus epidermidis commonly causes prosthetic device infections and affects immunocompromised individuals.
- Spontaneous pyomyositis from Staphylococcus epidermidis is rare.
- Kikuchi-Fujimoto disease (KFD) is a rare lymphadenitis, possibly triggered by a T-cell response to pathogens.
Observation:
- A patient presented with simultaneous spontaneous pyomyositis and Kikuchi-Fujimoto disease.
- The pyomyositis was caused by Staphylococcus epidermidis.
Findings:
- This case highlights an unusual co-occurrence of Staphylococcus epidermidis pyomyositis and Kikuchi-Fujimoto disease.
- The findings suggest a potential role for Staphylococcus epidermidis as a trigger for KFD.
Implications:
- This case expands the understanding of KFD pathogenesis.
- It suggests exploring infectious triggers like Staphylococcus epidermidis in KFD cases.
- Further research may elucidate the link between specific bacterial infections and KFD development.
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