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Updated: Jun 27, 2026
Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
Synthetic applications of polystyrene-supported 1,1,3,3-tetramethylguanidine
Alberto Coelho1, Abel Crespo, Franco Fernández
1Unidad de Química Combinatoria, Instituto de Farmacia Industrial (IFI), Facultad de Farmacia, Universidad de Santiago de Compostela, Santiago de Compostela, Spain.
Abstract:
Several applications of polystyrene-supported 1,1,3,3-tetramethylguanidine (PS-TMG) in synthetic organic chemistry have been explored. This study evidenced the effectiveness and versatility of this new member of the supported guanidine superbases as an attractive candidate to replace the bases usually employed in organic synthesis during the implementation of environmentally friendly preparative processes.
