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Updated: Jun 27, 2026

Non-invasive Parenchymal, Vascular and Metabolic High-frequency Ultrasound and Photoacoustic Rat Deep Brain Imaging
Published on: March 2, 2015
Ultrasound techniques for drug delivery in cardiovascular medicine
Luigi Landini1, Maria Filomena Santarelli, Linda Landini
1Department of Information Engineering, University of Pisa, Via Diostisalvi, 2, 56126 Pisa, Italy. llandini@ifc.cnr.it
Abstract:
In this review, we will give a critical update of published studies using ultrasound for targeted therapeutic use. We will briefly discuss the interaction mechanisms and their effects in non-invasive delivery of therapeutic agents. Moreover, the mechanisms by which ultrasonic contrast agents facilitate the delivery of drugs and genes into tissue will be discussed, together with recent applications and perspectives of targeted-microbubbles in cardiovascular medicine.
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