Related Experiment Video
Updated: Jun 27, 2026
07:42
Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Recent patents on molecular cytogenetics.
Ivan Y Iourov1, Svetlana G Vorsanova, Yuri B Yurov
1National Research Center of Mental Health, Russian Academy of Medical Sciences, Moscow, 119152, Russia.
Recent Patents on DNA & Gene Sequences
|December 17, 2008
Summary
This review examines worldwide patents on DNA sequences used as molecular cytogenetic probes and techniques. It highlights the need for a comprehensive understanding of patenting in this rapidly advancing biomedical field.
Area of Science:
- Biotechnology
- Genetics
- Intellectual Property Law
Background:
- Patenting of DNA sequences for specific proteins is well-documented.
- However, patenting of molecular cytogenetic techniques and their applications, particularly those using repetitive DNA or microdissected sequences, remains underexplored.
- Molecular cytogenetics is a widely used bioscience technique with over 40,000 publications referencing its methods.
Purpose of the Study:
- To review worldwide patents related to DNA sequences used as molecular cytogenetic probes.
- To analyze patents concerning molecular cytogenetic techniques themselves.
- To define the current landscape and future perspectives of patenting in this biomedical research area.
Main Methods:
- Systematic review of global patent databases.
- Analysis of patents focusing on DNA sequences used as probes in molecular cytogenetics.
- Examination of patents covering various molecular cytogenetic techniques, including those utilizing satellite DNA, telomeric DNA, and chromosome microdissection.
Main Results:
- Identified a gap in the literature regarding the patenting of molecular cytogenetic techniques and applications.
- Highlighted the increasing relevance of patenting DNA probes derived from repetitive genomic elements and microdissection.
- Underscored the general interest for researchers due to the widespread application of molecular cytogenetic techniques.
Conclusions:
- There is a need for comprehensive patent analysis in molecular cytogenetics.
- Understanding patent landscapes is crucial for researchers in biology and medicine.
- This review provides insights into the current state and future trends of patenting in molecular cytogenetics.
Related Concept Videos
01:17Karyotyping
Describing the number and physical features of chromosomes can reveal abnormalities that underlie genetic diseases. This description is facilitated by special staining techniques that produce a particular banding pattern on each chromosome. State-of-the-art techniques make this approach even more powerful, enabling the detection of individual genes that cause disease.A Simple Chromosome Staining Technique Provides Valuable Scientific InsightSome genetic diseases can be detected by looking at...
01:17Karyotyping
Describing the number and physical features of chromosomes can reveal abnormalities that underlie genetic diseases. This description is facilitated by special staining techniques that produce a particular banding pattern on each chromosome. State-of-the-art techniques make this approach even more powerful, enabling the detection of individual genes that cause disease.A Simple Chromosome Staining Technique Provides Valuable Scientific InsightSome genetic diseases can be detected by looking at...
01:29Modern Molecular Taxonomy
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
02:59Animal Mitochondrial Genetics
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
02:04Polytene Chromosomes
Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also regularly...
02:20Cohesins
Cohesin protein complexes are a molecular glue that holds two sister chromatids together. They play an important role both in mitosis and meiosis. In mitosis, all cohesin complexes present on the chromosomes are removed before the start of the anaphase stage.
Cohesin complexes in Meiotic Division
Meiosis involves two distinct rounds of chromosomal segregation and cell divisions— Meiosis I followed by Meiosis II – producing four daughter cells. Meiosis I includes the separation of homologous...
Cohesin complexes in Meiotic Division
Meiosis involves two distinct rounds of chromosomal segregation and cell divisions— Meiosis I followed by Meiosis II – producing four daughter cells. Meiosis I includes the separation of homologous...