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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

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Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...

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Related Experiment Video

Updated: Jun 27, 2026

Designing Porous Silicon Films as Carriers of Nerve Growth Factor

Designing Porous Silicon Films as Carriers of Nerve Growth Factor

Published on: January 25, 2019

Silicon based materials for drug delivery devices and implants.

Delia L Bernik¹

¹Institute of Physical Chemistry of Materials, Environment and Energy (INQUIMAE), School of Sciences, University of Buenos Aires, Buenos Aires, Argentina. dbernik@qi.fcen.uba.ar

Recent Patents on Nanotechnology

|December 17, 2008

Summary

This patent review highlights silicon-based materials for advanced medical applications. It covers silicon dioxide, silicones, and other compounds for drug delivery and tissue engineering implants.

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Area of Science:

Materials Science
Biomedical Engineering
Chemistry

Background:

Silicon-based materials are increasingly utilized in medical applications due to their versatile properties.
Patents reveal diverse silicon compounds for drug delivery and tissue engineering.
Understanding these patented innovations is crucial for future medical device development.

Purpose of the Study:

To review patents on silicon-based materials for medical applications, specifically drug delivery systems and implant devices.
To identify and describe representative silicon-based compounds and their applications.
To highlight the advantages of various silicon materials in patented inventions.

Main Methods:

Patent literature review focusing on silicon-based materials for medical use.
Categorization of silicon compounds into inorganic, organic, and hybrid types.
Analysis of patented inventions utilizing silicon dioxide, silica aerogels/xerogels, bioactive silicon materials, silicones, and ormosils.

Main Results:

Identification of key silicon-based materials including silicon dioxide, silica aerogels/xerogels, bioactive silicon materials, silicones, and ormosils.
Examples of patented drug delivery systems utilizing these materials for controlled release.
Examples of patented biomaterials for tissue engineering applications.
Demonstration of the specific benefits of each silicon compound type within different invention embodiments.

Conclusions:

Silicon-based materials offer a wide range of properties suitable for advanced medical applications.
Patented inventions showcase the significant potential of silicon compounds in drug delivery and tissue engineering.
Further research and development in silicon-based biomaterials will likely lead to novel medical devices and therapies.