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[Disproportionately high left ventricular myocardial mass in patients with arterial hypertension]

Zh D Kobalava, Iu V Kotovskaia, A F Safarova

    Kardiologiia
    |December 17, 2008
    PubMed

    Insights

    Disproportionately high left ventricular mass (DH MMLV) is common in patients with uncontrolled hypertension. This condition is linked to metabolic issues and subclinical heart problems.

    Area of Science:

    • Cardiology
    • Hypertension Research
    • Echocardiography

    Background:

    • Elevated arterial pressure can cause disproportionately high left ventricular mass (DH MMLV), a form of hypertrophy resistant to treatment.
    • This study investigates the prevalence and associated factors of DH MMLV in hypertensive patients.

    Purpose of the Study:

    • To determine the frequency of DH MMLV in patients with arterial hypertension (AH).
    • To identify factors associated with DH MMLV in this population.

    Main Methods:

    • Assessed 170 patients with untreated or irregularly treated AH.
    • Calculated the coefficient of disproportionality (CD) using actual to expected MMLV ratios.

    Main Results:

    • DH MMLV was observed in 82.4% of patients; LVH was only present in those with DH MMLV.
    • LVH frequency increased with the degree of MMLV disproportionality (18.9% to 82.2%).
    • DH MMLV correlated with higher BMI, metabolic disturbances, concentric LV geometry, and diastolic dysfunction.

    Conclusions:

    • DH MMLV is prevalent in uncontrolled hypertensive patients.
    • Assessing MMLV disproportionality offers additional insight into myocardial morphofunctional status.
    • DH MMLV is associated with subclinical cardiac issues and adverse metabolic changes.
    Abstract

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