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Updated: Jun 27, 2026

Preparation of Frozen Non-Human Primate Fetal Islets for Combined Single Nuclei RNA-Sequencing and ATAC-Sequencing, and Bulk Metabolomics
Published on: November 8, 2024
An overview of proteomic and metabolomic technologies and their application to pregnancy research
R P Horgan1, O H Clancy, J E Myers
1The Maternal and Fetal Health Research Centre, The University of Manchester, St Mary's Hospital, Whitworth Park, Manchester, UK.
Abstract:
'Omic' technologies represent a strategy towards high-throughput, simultaneous analysis of thousands of biological molecules. Their development has been accelerated in the post-genomic era since these molecules represent the interaction of genes and environment or the 'functional genome'. Omic domains are of particular interest in the search for predictive disease biomarkers and have additional relevance in understanding pathophysiology and the development of molecularly targeted therapeutics. This review examines the fields of proteomics and metabolomics in the context of obstetrics and gynaecology, including a discussion of methodology, challenges, potential applications and current research.
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