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Mitochondrial polymorphisms are associated both with increased and decreased longevity

Loredana Castri1, Mauricio Melendez-Obando, Ramon Villegas-Palma

  • 1Dipartimento di Biologia evoluzionistica sperimentale, Università di Bologna, Bologna, Italy.

Human Heredity
|December 17, 2008
PubMed
Summary

Mitochondrial DNA (mtDNA) affects human longevity, but birth era is a more significant factor. Specific mtDNA mutations like 5178A and 150T show varied associations with lifespan, with effects differing across time periods.

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