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[Ileal mucormycosis diagnosed by colonoscopy in a patient with acute myeloid leukemia]
Jae Yong Han1, Jae Hee Cheon, Duk Hwan Kim
1Departments of Internal Medicine,Yonsei University College of Medicine, Seoul, Korea.
Abstract:
Gastrointestinal mucormycosis is an uncommon opportunistic fungal infection often presents in immunocompromised patients. Direct invasion of the intestinal walls by spores from ingested food is the main pathogenetic mechanism of this disease, which usually takes place in stomach and colon. Early diagnosis is critical, especially in vascular invasive types, due to its high mortality rate close to 100%. In the past when appropriate diagnostic tools were not available, mucormycosis were frequently found with autopsy. The advance in current endoscopic technology has increased diagnostic rate and made successful management available with appropriate treatments such as debridement of contaminated tissues. In this case report, we discussed a case of ileal mucormycosis diagnosed by colonoscopy and treated with anti-fungal agent successfully.
Insights
Gastrointestinal mucormycosis, a rare fungal infection in immunocompromised individuals, requires early diagnosis for survival. This case highlights successful diagnosis via colonoscopy and treatment with antifungal agents.
Area of Science:
- Mycology
- Gastroenterology
- Infectious Diseases
Background:
- Gastrointestinal mucormycosis is a rare, opportunistic fungal infection primarily affecting immunocompromised patients.
- It typically involves direct invasion of intestinal walls by ingested fungal spores, commonly in the stomach and colon.
Observation:
- This case report details an instance of ileal mucormycosis.
- Diagnosis was achieved through advanced colonoscopy techniques.
Findings:
- The patient with ileal mucormycosis was successfully treated with antifungal medication.
- Early diagnosis through endoscopy improved patient outcomes, contrasting with historical autopsy findings.
Implications:
- Advances in endoscopic technology enhance the diagnostic rate of gastrointestinal mucormycosis.
- Prompt diagnosis and treatment, including surgical debridement and antifungal therapy, are crucial for managing this high-mortality condition.
