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Updated: Jun 27, 2026

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
Published on: December 22, 2015
Histological, histomorphometric, and radiographic evaluation of a sinus augmentation with a new bone allograft: a
Ricardo Gapski1, Carl Misch, David Stapleton
1GT International Implant Institute, Curitiba, Brazil. rgapski@pitimplant.com
Purpose:
This case report documents the histological, histomorphometric, and radiographic effects of a new radiated-preserved bone allograft for sinus elevation procedures.
Materials And Methods:
This unique bone substitute differs from other forms of bone allograft processed through the standard cryopreservation method. Histology from bone biopsy core samples revealed newly formed bone with a well-organized lamellar bone structure in general and remaining particles were observed in contact with surrounding newly-formed bone.
Results:
Histomorphometric results demonstrated an average new bone formation of 31.8%. Radiographic linear data demonstrated an 8.49% +/- 6.77% graft resorption from baseline to 6 months.
Conclusion:
The outcome of this report suggests that this bone allograft could be successfully used in sinus lifting procedures. It encourages further research of this radiated-preserved bone allograft material in oral and maxillofacial reconstruction.
