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Updated: Jun 27, 2026

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(Pro)renin receptors: are they biologically relevant?

A H Jan Danser1

  • 1Division of Pharmacology, Vascular and Metabolic Diseases, Department of Internal Medicine, Rotterdam, The Netherlands. a.danser@erasmusmc.nl

Current Opinion in Nephrology and Hypertension
|December 17, 2008
PubMed
Summary

The (pro)renin receptor activates prorenin, leading to angiotensin-independent signaling and potential hypertension. However, its precise biological role remains unclear due to conflicting data on antagonists.

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