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Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
Anatomy of Respiratory System I: Upper Respiratory Tract01:29

Anatomy of Respiratory System I: Upper Respiratory Tract

The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.

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Related Experiment Video

Updated: Jun 27, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Rhinosinusitis and asthma: the missing link.

Anne E Dixon1

  • 1Vermont Lung Center, Department of Medicine, University of Vermont, Burlington, Vermont 05405, USA. anne.dixon@uvm.edu

Current Opinion in Pulmonary Medicine
|December 17, 2008
PubMed
Summary
This summary is machine-generated.

Rhinitis and sinusitis are closely linked to asthma, often preceding it and worsening control. Treating upper airway disease may impact asthma, but more research is needed to confirm prevention and improved outcomes.

More Related Videos

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
11:54

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

Published on: January 21, 2018

Related Experiment Videos

Last Updated: Jun 27, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
11:54

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

Published on: January 21, 2018

Area of Science:

  • Respiratory medicine
  • Immunology
  • Epidemiology

Background:

  • Upper airway diseases like rhinitis and sinusitis are common comorbidities in asthma patients.
  • These conditions may represent a single disease process affecting both upper and lower airways.
  • Rhinitis often precedes the onset of asthma and is associated with poorer asthma control.

Purpose of the Study:

  • To review new findings on the epidemiological and pathophysiological links between upper and lower airways.
  • To assess the impact of treating sinonasal disease on asthma development and control.

Main Methods:

  • Literature review of recent epidemiological and pathophysiological studies.
  • Analysis of data on the effects of sinonasal disease treatment on asthma.

Main Results:

  • Rhinitis is prevalent in asthma and linked to worse asthma control.
  • Rhinitis frequently precedes asthma development, with evidence of subclinical lower airway changes.
  • Research is ongoing regarding the impact of allergic rhinitis treatment on asthma development.

Conclusions:

  • Rhinitis, sinusitis, and asthma are likely interconnected manifestations of a single disease process.
  • Treating rhinitis may influence airway obstruction but its effect on lower airway inflammation requires further study.
  • Prospective research is necessary to determine if rhinitis treatment can prevent asthma or improve outcomes in existing asthma.