Related Experiment Video
Updated: Jun 27, 2026

05:33
Using Modified Synthetic Oligonucleotides to Assay Nucleic Acid-Metabolizing Enzymes
Published on: July 5, 2024
Alfred nobel
1The author is a United States journalist who has worked in Sweden for many years as a writer-producer for Radio Sweden International and as a translator for Acta Radiologica and the Stockholm Institute of Education.
Summary
Alfred Nobel
Area of Science:
- Medical History
- Neurology
- Rheumatology
Background:
- Alfred Nobel's private health struggles were revealed through recently published letters.
- His writings detail decades of undiagnosed pain, fatigue, and migraines.
Purpose of the Study:
- To hypothesize Alfred Nobel's potential health conditions based on his personal correspondence.
- To explore the historical context of diagnosing chronic pain syndromes.
Main Methods:
- Analysis of 216 letters written by Alfred Nobel to his mistress over 18 years.
- Review of Nobel's descriptions of symptoms including pain, fatigue, and migraines.
Main Results:
- Nobel's symptoms align with potential fibromyalgia, though other conditions like angina pectoris were also present.
- He endured a 30-year diagnostic odyssey, facing skepticism and a lack of diagnosis for his persistent pain.
Conclusions:
- The subjective accounts suggest Nobel may have suffered from fibromyalgia, contributing to his later-life depression.
- Highlighting the challenges in diagnosing elusive syndromes like fibromyalgia, even for historical figures.
Related Concept Videos
Noble Gases
The elements in group 18 are noble gases (helium, neon, argon, krypton, xenon, and radon). They earned the name “noble” because they were assumed to be nonreactive since they have filled valence shells. In 1962, Dr. Neil Bartlett at the University of British Columbia proved this assumption to be false.
The DNA Helix
Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most viruses. DNA is composed of two strands of nucleotides that wind around each other to form a spring-like structure called a double helix. However, the double helix is not perfectly symmetrical. Instead, there are regularly occurring grooves in the structure. The major groove occurs where the sugar-phosphate backbones are relatively far apart. This space...
The DNA Helix
Overview
Altruism
Altruistic behaviors are “unselfish” behaviors—those that help another individual at the expense of the individual carrying out the behavior. Despite the negative consequences for the altruistic animal, these behaviors are thought to have evolved for several reasons.
Atomic Number and Mass Number
The number of protons in the nucleus of an atom is its atomic number (Z). This is the defining trait of an element. Its value determines the identity of the atom. For example, any atom that contains six protons is the element carbon and has the atomic number 6, regardless of how many neutrons or electrons it may have. A neutral atom must contain the same number of positive and negative charges, so the number of protons equals the number of electrons. This means that the atomic number also...
Subatomic Particles
Dalton was only partially correct about the particles that make up matter. All matter is composed of atoms, and atoms are composed of three smaller subatomic particles: protons, neutrons, and electrons. These three particles account for the mass and the charge of an atom.

