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A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection

A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection

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Reactive Arthritis Following Clostridium difficile Colitis in a 3-Year-Old Patient.

D R Finger¹, J V Neubauer

¹Rheumatology Service (D.R.F.) and Department of Medicine (J.V.N.), William Beaumont Army Medical Center, El Paso, Texas.

Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases

|December 17, 2008

Summary

This summary is machine-generated.

Reactive arthritis following Clostridium difficile (CD) colitis is rare in children. This case report details the first pediatric patient with this condition, highlighting its similar presentation to adult cases.

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A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection

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Published on: June 15, 2018

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Area of Science:

Pediatric Rheumatology
Infectious Diseases
Gastroenterology

Background:

Reactive arthritis following Clostridium difficile (CD) colitis is increasingly recognized in adults.
Twenty adult cases have been documented in medical literature.
This condition is rarely reported in pediatric patients.

Purpose of the Study:

To report the first pediatric case of reactive arthritis following CD colitis.
To describe the clinical features and outcomes of this condition in a child.
To compare pediatric and adult presentations of reactive arthritis post-CD colitis.

Main Methods:

Case report of a 3-year-old patient.
Review of clinical presentation, diagnostic findings, and treatment.
Comparison with existing literature on adult cases.

Main Results:

The patient, a 3-year-old, developed reactive arthritis after CD colitis.
Clinical features were similar to adult cases, including asymmetric oligoarticular arthritis of lower extremities.
Arthritis onset was 1-2 weeks post-diarrhea, with resolution in weeks to months.

Conclusions:

Reactive arthritis following CD colitis can occur in children, though likely less common than in adults.
Pediatric cases may present with fewer mucocutaneous manifestations.
Gastrointestinal pathogens are more frequent triggers in children compared to genitourinary organisms.