Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Acute Inflammation III: Local and Systemic Effects01:25

Acute Inflammation III: Local and Systemic Effects

Acute inflammation produces a coordinated set of local and systemic changes that limit injury, eliminate pathogens, and initiate repair. These responses arise within minutes of infection, trauma, or chemical insult and are driven by vascular alterations and leukocyte-derived mediators. When the stimulus resolves, the reaction typically abates within days.Local EffectsAt the site of injury, arteriolar vasodilation increases blood flow, resulting in redness and warmth. Simultaneously, increased...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Meeting of the Northeastern Indiana Medical Society.

Medical examiner (Chicago, Ill.)·2023
Same author

First Report of Anthracnose Fruit Rot Caused by Colletotrichum acutatum on Strawberry in Korea.

Plant disease·2019
Same author

Development of a Nested Polymerase Chain Reaction Assay for Detection of Colletotrichum acutatum on Symptomless Strawberry Leaves.

Plant disease·2019
Same author

Climate change and the integrity of science.

Science (New York, N.Y.)·2010
Same author

Pseudoplasticity and setting properties of two-solution bone cement containing poly(methyl methacrylate) microspheres and nanospheres for kyphoplasty and vertebroplasty.

Journal of biomedical materials research. Part B, Applied biomaterials·2009
Same author

Subacute bacterial endocarditis with polyarthritis mimicking thrombotic thrombocytopenic purpura: a case report.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2008
Same journal

Risk of Femoral Head Osteonecrosis Following Hip Trauma in Adults With Systemic Lupus Erythematosus.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2026
Same journal

Efficacy and Safety of Intravenous Golimumab in Patients With Ankylosing Spondylitis and Complete Spinal Ankylosis: Results Through Week 52 of the GO-ALIVE Study: Erratum.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2026
Same journal

Efficacy and Safety of Intravenous Golimumab in Ankylosing Spondylitis Patients With Early and Late Disease Through One Year of the GO-ALIVE Study: Erratum.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2026
Same journal

Microbiome Dysbiosis as a Potential Driver of Inflammatory Mimicry in Pachydermoperiostosis-associated Hypertrophic Osteoarthropathy.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2026
Same journal

Understanding Gaps in Methotrexate Education in the Adolescent and Young Adult Population.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2026
Same journal

Prevalence of Attention Deficit Hyperactivity Disorder in Adult Patients With Fibromyalgia.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2026
See all related articles

Related Experiment Video

Updated: Jun 27, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Giant Cell Arteritis in AJ Americans.

J L Gilbert, M D Coe, M H Nam

    Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases
    |December 17, 2008
    PubMed
    Summary
    This summary is machine-generated.

    Giant cell arteritis (GCA) presents differently in African Americans, with more male patients, anemia, and visual loss. Early diagnosis of GCA is crucial for all patients, regardless of race, to prevent vision loss.

    Related Experiment Videos

    Last Updated: Jun 27, 2026

    An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
    06:35

    An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

    Published on: February 8, 2019

    Area of Science:

    • Rheumatology
    • Vasculitis
    • Epidemiology

    Background:

    • Giant cell arteritis (GCA) is typically considered less prevalent in African Americans.
    • Previous studies have suggested racial variations in GCA presentation and outcomes.

    Purpose of the Study:

    • To investigate the clinical characteristics and outcomes of biopsy-proven GCA in African Americans.
    • To compare the presentation of GCA in African Americans with a Caucasian cohort.

    Main Methods:

    • Retrospective review of 9 African American patients with biopsy-proven GCA at the Washington Hospital Center (1988-1996).
    • Combined data with 41 previously published African American patients.
    • Compared findings with a representative Caucasian cohort.

    Main Results:

    • African American patients more frequently presented with male gender, anemia, and visual loss compared to Caucasians.
    • Constitutional symptoms and polymyalgia rheumatica were less common in African Americans.
    • Temporal artery biopsy detection rates did not differ by race.

    Conclusions:

    • Giant cell arteritis should be considered in all patients with suggestive clinical features, irrespective of race.
    • Earlier GCA recognition may contribute to a reduced incidence of permanent visual loss.