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Published on: May 6, 2018
Rhabdomyolysis associated with nutritional supplement use
D A Scroggie1, M Harris, L Sakai
1Wilford Hall Medical Center, Lackland AFB, Texas; Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Nutritional supplements like Diet Fuel and GlutaMASS may cause rhabdomyolysis, a serious muscle injury, in young men undergoing regular training. Increased supplement use correlates with higher toxicity risks.
Area of Science:
- Sports Medicine
- Toxicology
- Nutritional Science
Background:
- Alternative medicine use has risen in the US over 20 years.
- Increased supplement consumption raises concerns about potential toxicity.
- Nutritional supplements are widely used by athletes and fitness enthusiasts.
Purpose of the Study:
- To report two cases of rhabdomyolysis linked to specific nutritional supplements.
- To investigate the potential link between supplement use and severe muscle injury.
- To raise awareness of adverse events associated with popular dietary products.
Main Methods:
- Case report of two young males experiencing rhabdomyolysis.
- Literature review on supplement-induced adverse events.
- Analysis of U.S. Food and Drug Administration (FDA) adverse event database.
Main Results:
- Two healthy young males developed rhabdomyolysis after using Diet Fuel and GlutaMASS.
- Literature and FDA data show multiple serious adverse events linked to these supplements and ingredients.
- A correlation between supplement intake and strenuous physical activity was observed.
Conclusions:
- Diet Fuel and GlutaMASS may contribute to rhabdomyolysis in individuals engaged in physical training.
- The combination of certain supplements and exercise may lead to significant muscle damage.
- Further investigation into supplement safety and potential interactions with physical activity is warranted.
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