Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bacterial Phylum Actinobacteria

Bacterial Phylum Actinobacteria

Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...

Cytoskeletal Proteins in Bacteria

Cytoskeletal Proteins in Bacteria

Bacterial cells were initially considered simple, randomly organized structures lacking a cytoskeleton. However, the discovery of cytoskeleton homologs in bacteria led to the change of this opinion. Bacterial cytoskeletal filaments regulate the cell shape, cell polarity, cell division, and partitioning of plasmids during cell division. It was later discovered that bacterial cytoskeletal proteins, mainly actin and tubulin homologs, are diverse compared to their eukaryotic counterparts. On the...

Bacterial Phylum Planctomycetes

Bacterial Phylum Planctomycetes

Planctomycetes are a group of morphologically distinct bacteria predominantly classified into two orders: Planctomycetales and Brocadiales. These gram-negative bacteria exhibit unique features, including division by budding and the presence of stalks or appendages. Their cells are often found in rosette arrangements, and they are notable for possessing an S-layer in their cell envelope, which is relatively uncommon among bacteria. Additionally, Planctomycetes frequently exhibit intracellular...

Microbial Morphologies

Microbial Morphologies

Bacterial and archaeal cells exhibit remarkable diversity in shape and structure, critical in their adaptability and functionality. Among bacteria, the most commonly observed shapes include cocci and bacilli. Cocci are spherical and may exist singly or in groupings such as pairs (diplococci), chains (streptococci), clusters (staphylococci), or tetrads. Bacilli, in contrast, are rod-shaped and can also occur as single cells, in pairs, or chains, depending on their environmental and genetic...

Diversity of Protists IV

Diversity of Protists IV

Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...

Fimbriae, Pili, and Axial Filaments

Fimbriae, Pili, and Axial Filaments

Fimbriae and pili are specialized bacterial surface structures that play pivotal roles in adhesion, genetic exchange, and motility. Composed primarily of pilin protein, these hairlike appendages are crucial for bacterial survival and pathogenicity in various environments.Fimbriae: Adhesion and PathogenicityFimbriae are fine, filamentous structures measuring 2–10 nanometers in diameter and are densely distributed on the bacterial cell surface. They facilitate bacterial adhesion to abiotic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dual-function enzyme acts as a global c-di-GMP sink and local anti sigma factor antagonist to drive cellular differentiation.

PLoS genetics·2026

Same author

A histidine pseudokinase modulates polar growth and cell shape in Streptomyces venezuelae.

Communications biology·2026

Same author

<i>Streptomyces</i> Volatiles Alter Auxin/Cytokinin Signaling, Root Architecture, and Growth Rate in <i>Arabidopsis thaliana</i> via Signaling Through the <i>KISS ME DEADLY</i> Gene Family.

Plants (Basel, Switzerland)·2026

Same author

Essential and dispensable domains of DivIVA for walled growth in filamentous Actinomycetota.

Open biology·2025

Same author

Gene sco1417 encodes a positive regulator of the de novo biosynthesis of pyridoxal 5'-phosphate (vitamin B6) in Streptomyces coelicolor M145.

BMC microbiology·2025

Same author

Deletion of <i>fbiC</i> in <i>Streptomyces venezuelae</i> removes autofluorescence in the excitation-emission range of cyan fluorescent protein.

Microbiology (Reading, England)·2025

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants

Published on: September 12, 2018

Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium.

Klas Flärdh¹, Mark J Buttner

¹Department of Cell and Organism Biology, Lund University, Lund, Sweden. mark.buttner@bbsrc.ac.uk

Nature Reviews. Microbiology

|December 17, 2008

Summary

Streptomyces bacteria exhibit complex multicellular behavior during their life cycle, involving coordinated growth, cell division, and secondary metabolism. This includes forming aerial mycelia and producing specialized structures for survival.

More Related Videos

Fluorescence Time-lapse Imaging of the Complete S. venezuelae Life Cycle Using a Microfluidic Device

Fluorescence Time-lapse Imaging of the Complete S. venezuelae Life Cycle Using a Microfluidic Device

Published on: February 28, 2016

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host

Published on: October 12, 2022

Related Experiment Videos

Last Updated: Jun 27, 2026

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants

Published on: September 12, 2018

Fluorescence Time-lapse Imaging of the Complete S. venezuelae Life Cycle Using a Microfluidic Device

Fluorescence Time-lapse Imaging of the Complete S. venezuelae Life Cycle Using a Microfluidic Device

Published on: February 28, 2016

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host

Published on: October 12, 2022

Area of Science:

Microbiology
Molecular Biology
Developmental Biology

Background:

Filamentous bacteria Streptomyces undergo morphological differentiation during their life cycle.
This differentiation is linked to growth, cell division, and complex multicellular behaviors.

Purpose of the Study:

To elucidate the intricate processes of morphological differentiation in Streptomyces.
To understand the coordination between cell-cycle events and multicellular development.

Main Methods:

Analysis of Streptomyces life cycle.
Investigation of cellular machinery reorganization during sporulation.
Study of extracellular signaling mechanisms.

Main Results:

Morphological differentiation is integrated with fundamental growth and cell-cycle processes.
Complex multicellular behavior involves hormone-like signaling and secondary metabolism.
Sporulation involves reorganization of cytoskeleton, cell-wall assembly, cell division, and chromosome segregation.

Conclusions:

Streptomyces exhibit unusual developmental programs, including aerial mycelium formation.
Production of surfactant peptides and hydrophobic sheaths aids survival by overcoming surface tension.
The study highlights the complexity of Streptomyces differentiation and adaptation.