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A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation
Published on: August 30, 2017
Detrimental effects of speckle-pixel size matching in laser speckle contrast imaging
Sean J Kirkpatrick1, Donald D Duncan, Elaine M Wells-Gray
1Divisionof Biomedical Engineering, Oregon Health & Science University, Portland, OR 97239, USA. skirkpat@bme.ogi.edu
Abstract:
Through a series of simulations and experiments, we demonstrate that the frequently cited criterion of matching speckle size to detector element (pixel) size in laser speckle contrast imaging (LSCI) has the detrimental effect of reducing the contrast and thereby decreasing the variation in the laser speckle contrast image. Unlike quasi-elastic light scattering, where this matching condition has been shown to maximize the signal-to-noise ratio, in LSCI, the minimum speckle size must exceed the Nyquist criterion in order to maximize the contrast of the speckle patterns.
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