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Related Experiment Video

Updated: Jun 27, 2026

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

Published on: August 22, 2014

Does physical exercise modify antioxidant requirements?

I Margaritis¹, A S Rousseau

¹French Food Safety Agency, Department for Evaluation of Nutritional and Health Risk, Maisons-Alfort, France.

Nutrition Research Reviews

|December 17, 2008

Summary

Athletes’ antioxidant needs increase with training, but high-dose supplements may harm adaptation. A balanced diet is key for optimal antioxidant status and performance.

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Last Updated: Jun 27, 2026

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

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Published on: August 22, 2014

Activating Autophagy by Aerobic Exercise in Mice

Activating Autophagy by Aerobic Exercise in Mice

Published on: February 3, 2017

Area of Science:

Exercise Physiology
Nutritional Biochemistry
Sports Science

Background:

Physical training induces biochemical adaptations, potentially increasing micronutrient needs.
The impact of exercise on antioxidant requirements remains a key question in sports nutrition.

Purpose of the Study:

To review studies on antioxidant micronutrient intake and exercise adaptation.
To explore athlete antioxidant requirements, considering training load and nutrition.
To analyze the risks and benefits of antioxidant supplementation.

Main Methods:

Literature review of crucial studies on exercise and antioxidant systems.
Interpretation of relationships between antioxidant intake and adaptive responses.
Analysis of training-load interactions with nutritional strategies.

Main Results:

Antioxidant supplements show no convincing effects in well-trained athletes.
High doses can have adverse effects, including pro-oxidant activity or impaired adaptation.
Supplement effects are primarily observed in cases of nutritional deficiency.

Conclusions:

Antioxidant needs can be met through a diversified, balanced diet tailored to individual requirements.
Supranutritional intakes pose unknown risks, potentially impairing training adaptations.
Focusing on nutrient-dense foods is recommended over low-density micronutrient products.