[The prevalence and risk factors for coronary stenosis in patients with cerebral infarction]

Jiang-hong Zheng1, Dong-qing Hu, Guang-yu An

  • 1Department and Interventional Therapy, Zhangye People's Hospital in Gansu Province, Zhangye 734000, China.

Zhonghua Nei Ke Za Zhi
|December 17, 2008
PubMed

Insights

Coronary stenosis affects nearly half of patients with cerebral infarction. Early heart screening is crucial for those over 65, with hypertension, or hyperlipidemia to detect this condition.

Area of Science:

  • Cardiology
  • Neurology
  • Radiology

Background:

  • Cerebral infarction (stroke) is a significant health concern.
  • Coronary artery disease is a common comorbidity.

Purpose of the Study:

  • To determine the prevalence of coronary stenosis in patients diagnosed with cerebral infarction.
  • To identify risk factors associated with coronary stenosis in this patient group.

Main Methods:

  • 112 patients with cerebral infarction underwent CT coronary angiography.
  • Multivariate logistic regression analysis was used to assess correlations between clinical data and coronary stenosis.

Main Results:

  • The morbidity rate of coronary stenosis was 46.4% in the overall cohort and 51.6% in a subgroup of 95 cerebral infarction patients.
  • Independent predictors for coronary stenosis included advanced age (>65 years), hypertension, hyperlipidemia, and significant cerebral artery narrowing.

Conclusions:

  • Routine cardiac CT screening is recommended for cerebral infarction patients post-cerebral angiography.
  • Early detection of coronary stenosis is particularly important for elderly patients with hypertension, hyperlipidemia, and cerebral artery disease.
Abstract

Related Concept Videos

Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...