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Updated: Jun 27, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
[Clinical analysis of 40 cases of pulmonary aspergilloma]
1Wuhan Tuberculosis Hospital, Wuhan 430083, China.
Objective:
To describe the treatment and diagnosis of pulmonary aspergilloma.
Methods:
The clinical data of 40 cases of pulmonary aspergilloma were analyzed.
Results:
There were 24 men and 16 women, aged 16-61 years. There were 37 cases with pulmonary tuberculosis with cavity or bronchiectasis Hemoptysis, cough, fever and sweat were present in 33, 5, and 3 cases respectively. The discontinuity repeatedly haemoptysis with a little (< 20 ml/time) were 27 cases. A correct diagnosis of aspergilloma was made in 60% cases (n = 24) before surgery. Lobectomy was performed in 39 cases, and unilateral lung removal in 1 case. Following surgery, 39 cases were cured, and 1 case died.
Conclusion:
Pulmonary aspergilloma occurs mostly in middle-aged patients with cavitary or bronchiectatic pulmonary tuberculosis. Misdiagnosis of both the underlying tuberculosis and aspergilloma was common before surgery. Surgery is indicated for patients with heavy hemoptysis, but the value of antifungal therapy needs further studies.
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