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Updated: Jun 27, 2026

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
Treatment of unruptured intracranial aneurysms: surgery, coiling, or nothing?
Joseph D Burns1, Robert D Brown
1Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Abstract:
The decision of whether and how to treat an unruptured intracranial aneurysm (UIA) is complex. The goal in caring for patients with UIAs is to maximize their duration of high-quality life by optimally balancing the risks of aneurysm rupture--the "natural history" of the aneurysm--with those of treatment-related adverse outcomes. In this article, we review the literature concerning the natural history of UIAs and summarize the procedure-associated morbidity and mortality and efficacy of surgical clipping and endovascular coiling. Using this information, we make recommendations regarding the optimal management of patients with UIAs.
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