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Updated: Jun 27, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Epidemiological study in patients with nasal polyposis]
Adolfo Toledano Muñoz1, Carlos Herráiz Puchol, Cristina Navas Molinero
1Unidad Otorrinolaringología, Fundación Hospital Alcorcón, Madrid, España. atoledano@fhalcorcon.es
Objective:
To investigate the epidemiologic data in 165 patients suffering nasal polyposis.
Material And Method:
We collected different variables that included age, gender, asthma, ASA sensitive, allergic rhinitis, smoker, drinker, familiar history. We studied the main symptoms (nasal blockage, rhinorrhea, anosmia, and headache) as well as otological and dermatological involvement.
Results:
Nasal polyposis affects men (63%) more frequently, with a mean age of 46.5 years. Asthma was found in 36.6 % of patients with nasal polyposis. The most frequent symptom was nasal blockage (88 %) followed by anosmia (78 %). Ears were affected in 42 % of patients and 20 % of first-degree relatives also suffer the same condition.
Conclusions:
Nasal polyposis affects both genders in middle age and may have an associated genetic factor in some patients. We must rule out asthma in all these patients.
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