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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Types02:20

Blood Types

Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
Blood Typing01:10

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
The ABO Blood Group01:12

The ABO Blood Group

The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...

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Related Experiment Video

Updated: Jun 27, 2026

Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols
11:31

Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols

Published on: January 2, 2013

Globalisation and blood safety.

Albert Farrugia1

  • 1Blood and Tissues Unit, Australian Therapeutic Goods Administration, ACT, Australia. albertfarrugia@hotmail.com

Blood Reviews
|December 17, 2008
PubMed
Summary
This summary is machine-generated.

Globalisation impacts blood safety through rapid pathogen spread and industry consolidation. Managing risks requires an integrated approach, not just product safety, to ensure a secure blood supply.

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Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
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Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

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Last Updated: Jun 27, 2026

Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols
11:31

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Published on: January 2, 2013

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

Area of Science:

  • Transfusion Medicine
  • Public Health
  • Epidemiology

Background:

  • Globalisation increases cross-border transactions and technology diffusion, impacting public health.
  • Globalisation affects blood safety through rapid spread of blood-borne pathogens and industry consolidation.
  • Modern travel facilitates swift pathogen transmission, posing risks before countermeasures can be implemented.

Purpose of the Study:

  • To analyze the multifaceted impacts of globalisation on blood safety and supply.
  • To explore the challenges posed by globalisation to traditional blood safety paradigms.
  • To advocate for an integrated risk management approach in transfusion medicine.

Main Methods:

  • Literature review and analysis of globalisation's effects on pathogen transmission.
  • Examination of industry trends, including plasma product rationalization and technology monopolization.
  • Case study analysis of globalisation-induced risks like West Nile Virus (WNV) and variant Creutzfeldt-Jakob disease (vCJD).

Main Results:

  • Globalisation accelerates the spread of blood-borne diseases, exemplified by West Nile Virus.
  • Industry consolidation and technology access limitations present challenges to blood product safety and supply.
  • Donor deferral measures for globalisation-related risks reduce the safest donor pool, increasing supply risks.

Conclusions:

  • Globalisation necessitates a shift from a zero-risk paradigm to an integrated process view for blood safety.
  • Effective risk management, rather than elimination, is crucial for overcoming globalisation's challenges in transfusion medicine.
  • An integrated approach is vital to maintain blood safety and supply amidst global interconnectedness.