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05:59
Nasal Wipes for Influenza A Virus Detection and Isolation from Swine
Published on: December 4, 2015
Swine influenza viruses a North American perspective
Amy L Vincent1, Wenjun Ma, Kelly M Lager
1Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa 50010, USA.
Advances in Virus Research
|December 17, 2008
Summary
Swine influenza (SI) is a global zoonotic threat. Recent dynamic evolution of swine influenza virus (SIV) subtypes in North America necessitates innovative control strategies and vaccine development.
Area of Science:
- Veterinary Virology
- Zoonotic Diseases
- Epidemiology
Background:
- Swine influenza (SI) is a significant zoonotic viral disease impacting global health and economies.
- First identified in pigs in 1918, SI has remained a persistent concern for the swine industry worldwide.
- The epidemiology of swine influenza virus (SIV) in North American pigs has evolved significantly.
Purpose of the Study:
- To review the epidemiology of swine influenza virus (SIV) infection in North American pigs.
- To discuss challenges and innovative strategies for controlling SI due to emerging subtypes.
- To explore protective immune responses and new vaccine development paradigms for SIV.
Main Methods:
- Review of epidemiological data on swine influenza virus (SIV) in North America.
- Analysis of the evolution of SIV subtypes and genetic variants.
- Discussion of current and potential control strategies, including immune responses and vaccine development.
Main Results:
- Swine influenza epidemiology has shifted from static to dynamic over the last decade with numerous emerging SIV subtypes.
- Increasing genetic diversity of SIV poses significant challenges for disease control.
- Current prophylactic approaches may have limited efficacy against evolving SIV strains.
Conclusions:
- The dynamic evolution of SIV in North American pigs is expected to continue.
- Innovative strategies are critical to combat the health and economic threats posed by SI.
- New vaccine development paradigms are essential for effective control and mitigation of economic losses.
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