Constipation is associated with spina bifida occulta in children
Zhengwei Yuan1, Wei Cheng, Ana Hou
1Department of Pediatric Surgery, Shengjing Hospital, China Medical University, Shenyang, China. yuanzw@hotmail.com
Insights
Spina bifida occulta (SBO) is more common in children with constipation. Biofeedback and electrical stimulation effectively treat SBO-related constipation symptoms and improve anorectal function.
Area of Science:
- Pediatric Gastroenterology
- Neurodevelopmental Disorders
- Urology
Background:
- Spina bifida occulta (SBO) is a frequent developmental anomaly.
- The relationship between SBO and pediatric constipation requires further investigation.
Purpose of the Study:
- To investigate the association between SBO and constipation in children.
- To evaluate the efficacy of biofeedback and electrical stimulation in managing SBO-related constipation.
Main Methods:
- 113 children with constipation underwent diagnostic tests including radiography, manometry, and neurophysiologic studies.
- SBO incidence in constipation groups (functional constipation and nonretentive fecal incontinence) was compared to controls.
- 24 children with SBO and constipation received biofeedback and electrical stimulation therapy.
Main Results:
- SBO was found in 47.7% of functional constipation cases and 77.8% of nonretentive fecal incontinence cases, significantly higher than controls (23.9%).
- Children with SBO exhibited altered anorectal function, including reduced rectal sensory thresholds and prolonged reflex latency.
- Biofeedback and electrical stimulation led to sustained symptomatic improvement in 79.2% of treated children.
Conclusions:
- Pediatric constipation is linked to a higher prevalence of SBO.
- Combined biofeedback and electrical stimulation therapy offers a promising treatment for SBO-associated constipation, improving both symptoms and objective functional measures.
Background & Aims:
Spina bifida occulta (SBO) is a common developmental variant. The aim of this study was to re-examine the possible association between SBO and constipation in children.
Methods:
A total of 113 children with constipation underwent plain abdominal radiography, anorectal manometry, neurophysiologic study, electromyography testing, and colonic transit study. Eighty-six were diagnosed with functional constipation (FC) and 27 were diagnosed with nonretentive fecal incontinence (NRFI). The incidence of SBO in these children was compared with 226 sex- and age-matched controls. Twenty-four SBO children with either FC or NRFI also underwent individualized biofeedback training and electric stimulation therapy based on the investigation results.
Results:
The incidence of SBO in the FC and NRFI groups was 47.7% and 77.8%, respectively. Statistically, this is significantly higher than that of the control group (chi-square, 23.9%; P < .05). Compared with the FC or NRFI children without SBO, the FC and NRFI children with SBO had decreased vector volumes and electromyography amplitudes, increased rectal sensory thresholds, and prolonged latency of pudendo-anal reflex. All 24 children who underwent individualized biofeedback training and electrical stimulation treatment had sustained symptomatic improvement with less straining, fewer incomplete bowel movements, and less abdominal pain. The recovery rate was 79.2% (19 of 24).
Conclusions:
Constipation in children is associated with increased incidence of SBO. Individualized biofeedback combined with electrical stimulation improves both the symptoms and the objective anorectal function measurements.
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