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Related Concept Videos

Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
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Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
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Acute Pharyngitis

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Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
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Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
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Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...

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Studying Oxidative Stress Caused by the Mitis Group Streptococci in Caenorhabditis elegans
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Studying Oxidative Stress Caused by the Mitis Group Streptococci in Caenorhabditis elegans

Published on: March 23, 2019

Serratia marcescens causing cervical necrotizing oropharyngitis.

Melissa M Statham1, Amit Vohra, Deepak K Mehta

  • 1University of Cincinnati School of Medicine, Department of Otolaryngology - Head and Neck Surgery, 231 Albert Sabin Way Cincinnati, OH 45267-0528, USA. mamcca025@yahoo.com

International Journal of Pediatric Otorhinolaryngology
|December 17, 2008
PubMed
Summary
This summary is machine-generated.

A rare Serratia marcescens infection caused severe necrotizing oropharyngitis in a child. A double-balloon dilatation technique successfully managed resulting hypopharyngeal stenosis, aiding function.

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Last Updated: Jun 27, 2026

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Published on: March 23, 2019

Area of Science:

  • Infectious Diseases
  • Otolaryngology
  • Pediatric Surgery

Background:

  • Necrotizing fasciitis is a severe soft tissue infection, rarely affecting the oropharynx.
  • Serratia marcescens is an opportunistic pathogen that can cause serious infections.

Observation:

  • A previously immunocompetent 6-year-old male presented with necrotizing oropharyngitis due to Serratia marcescens.
  • The infection resulted in a near-total oropharyngeal defect and subsequent nasopharyngeal and hypopharyngeal stenoses.

Findings:

  • The oropharyngeal wound was managed with debridement, carotid artery coverage, and pharyngeal packing.
  • The patient's hypopharyngeal stenosis was successfully treated using a minimally invasive double-balloon dilatation technique.

Implications:

  • This case highlights Serratia marcescens as a cause of severe necrotizing oropharyngitis in immunocompetent children.
  • Minimally invasive double-balloon dilatation offers a viable option for managing pediatric hypopharyngeal stenosis post-infection.
  • Restoration of function for voicing and deglutition remains a challenge in complex oropharyngeal defects.