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Related Concept Videos

Electrocardiogram01:29

Electrocardiogram

An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...

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Related Experiment Video

Updated: Jun 27, 2026

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System
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Electrocardiographic and echocardiographic changes in perinatal asphyxia.

P S Rajakumar1, B Vishnu Bhat, M G Sridhar

  • 1Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Indian Journal of Pediatrics
|December 17, 2008
PubMed
Summary

Cardiac troponin-T assays effectively evaluate myocardial damage in newborns experiencing perinatal asphyxia. This cardiac enzyme measurement correlates with disease severity and patient outcomes, offering a valuable diagnostic tool.

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Last Updated: Jun 27, 2026

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07:34

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Published on: May 5, 2018

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10:55

A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation

Published on: January 13, 2023

Area of Science:

  • Neonatal Medicine
  • Cardiology
  • Biochemistry

Background:

  • Perinatal asphyxia poses a significant risk of myocardial damage in term infants.
  • Accurate assessment of cardiac involvement is crucial for predicting outcomes.

Purpose of the Study:

  • To determine the utility of cardiac enzymes, specifically troponin-T and CK-MB, in assessing myocardial injury in perinatal asphyxia.
  • To compare the diagnostic performance of troponin-T and CK-MB.

Main Methods:

  • A case-control study involving 30 term infants with perinatal asphyxia and 30 healthy controls.
  • Evaluation of myocardial dysfunction through clinical assessment, ECG, echocardiography, and measurement of cardiac enzymes (troponin-T, CK-MB).

Main Results:

  • Elevated cardiac enzyme levels were observed in infants with perinatal asphyxia compared to controls.
  • Troponin-T demonstrated higher sensitivity and specificity than CK-MB in detecting myocardial involvement.
  • Troponin-T levels correlated significantly with the severity and clinical outcome of perinatal asphyxia.

Conclusions:

  • Cardiac troponin-T assay is a valuable tool for assessing the severity of myocardial damage in perinatal asphyxia.
  • Troponin-T levels can aid in predicting the outcome for affected neonates.