Related Experiment Video
Updated: Jun 27, 2026
09:04
Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform
Published on: January 30, 2017
The Pig Genome Database (PiGenome): an integrated database for pig genome research
Dajeong Lim1, Yong-Min Cho, Kyung-Tai Lee
1Department of Agricultural Biotechnology, Seoul National University (SNU), Seoul, 151-742, South Korea.
Summary
The Pig Genome Database (PiGenome) integrates pig genome data, including expressed sequence tags (ESTs) and quantitative trait loci (QTLs). This resource aids pig genome research by providing advanced analysis and comparative mapping tools.
Area of Science:
- Genomics
- Bioinformatics
Background:
- The pig genome is crucial for agricultural and biomedical research.
- Integrating diverse genomic data is essential for comprehensive pig genome analysis.
Purpose of the Study:
- To establish a centralized database, PiGenome, for comprehensive pig genome research.
- To integrate and analyze publicly available pig genome-wide data and newly generated sequences.
Main Methods:
- Integrated public data: UniGenes, STS markers, QTLs, BAC contigs.
- Generated and incorporated new data: 69,545 ESTs and 182 BAC contig sequences.
- Clustered and assembled EST data; collected QTL and marker information from public databases.
Main Results:
- The PiGenome database now includes integrated genome-wide data and new sequences.
- Provided functional annotation, transcript identification, coding sequence mapping, and SNP information.
- Developed advanced search, disease browser, alternative splicing, and comparative gene map features.
Conclusions:
- PiGenome offers a valuable, integrated resource for pig genome research.
- The database facilitates advanced analysis, visualization, and comparative genomics in pigs.
More Related Videos
Related Concept Videos
02:02Genomics
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
02:57piRNA - Piwi-interacting RNAs
PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...
03:36Genome Annotation and Assembly
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.