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Updated: Jun 27, 2026

Methodology for Accurate Detection of Mitochondrial DNA Methylation
Published on: May 20, 2018
A database of mitochondrial DNA hypervariable regions I and II sequences of individuals from Slovakia
Ivan Lehocký1, Marian Baldovic, Ludevít Kádasi
1Department of Forensic Biology and DNA Analyse, Institute of Forensic Science of Police Corps, Bratislava, Slovak Republic. lehocky@keupz.minv.sk
Abstract:
In order to identify polymorphic positions and to determine their frequencies and the frequency of haplotypes in the human mitochondrial control region, two hypervariable regions (HV1 and HV2) of the mitochondrial DNA (mtDNA) of 374 unrelated individuals from Slovakia were amplified and sequenced. Sequence comparison led to the identification of 284 mitochondrial lineages as defined by 163 variable sites. Genetic diversity (GD) was estimated at 0.997 and the probability of two randomly selected individuals from population having identical mtDNA types (random match probability, RMP) for the both regions is 0.60%.
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