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16 STR data of a Greek population.

P Sánchez-Diz1, P G Menounos, A Carracedo

  • 1Institute of Legal Medicine, Genomics Medicine Group, University of Santiago de Compostela, Santiago de Compostela, Spain. paulaiml@usc.es

Forensic Science International. Genetics
|December 17, 2008
PubMed
Summary

Forensic geneticists analyzed 16 short tandem repeat (STR) loci in 300 Greeks. High discriminatory power was found, supporting its use in forensic DNA identification.

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Area of Science:

  • Forensic Genetics
  • Population Genetics
  • Human Identification

Background:

  • Short tandem repeat (STR) loci are crucial for human identification.
  • Understanding allele frequencies in specific populations is essential for forensic applications.

Purpose of the Study:

  • To determine the allele frequencies of 16 STR loci in the Greek population.
  • To evaluate the forensic efficiency of these STR loci for individual identification.

Main Methods:

  • Analysis of 16 STR loci (including D8S1179, D21S11, SE33) in 300 unrelated Greek individuals.
  • Calculation of allele frequencies and assessment of Hardy-Weinberg equilibrium.
  • Determination of combined power of discrimination (PD) and power of exclusion (PE).

Main Results:

  • Allele frequencies for 16 STR loci were established for the Greek sample.
  • No deviations from Hardy-Weinberg equilibrium were observed, indicating population stability.
  • The combined PD and PE values were exceptionally high (0.999999999 and 0.999999816), demonstrating strong discriminatory power.

Conclusions:

  • The 16 STR loci are highly informative and suitable for forensic identification in the Greek population.
  • Low genetic distances suggest genetic similarity with neighboring European populations.
  • This dataset enhances the reliability of DNA profiling for forensic casework in Greece.