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Related Experiment Video

Updated: Jun 27, 2026

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease

Published on: February 8, 2022

Multidetector computed tomography shows intramyocardial fat deposition.

Aidan R Raney¹, Farhood Saremi, Satish Kenchaiah

¹Department of Radiologic Sciences, University of California, Irvine, Orange, CA 92868-3298, USA.

Journal of Cardiovascular Computed Tomography

|December 17, 2008

Summary

This summary is machine-generated.

Intramyocardial fat deposition is common in healthy and diseased hearts, detectable by multidetector computed tomography (MDCT). Older age and male sex are associated with increased intramyocardial fat, particularly in the right ventricle and left ventricle, respectively.

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In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

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Published on: February 16, 2016

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Last Updated: Jun 27, 2026

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease

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Published on: February 8, 2022

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Area of Science:

Cardiology
Medical Imaging
Pathology

Background:

Intramyocardial fat deposition is an age-related phenomenon.
It is also associated with various pathological conditions.
Understanding its distribution and predictors is crucial for cardiac health assessment.

Purpose of the Study:

To evaluate the presence and distribution of left ventricular (LV) and right ventricular (RV) intramyocardial fat.
To assess the utility of 64-slice multidetector computed tomography (MDCT) for detecting intramyocardial fat.
To investigate associations between intramyocardial fat, age, sex, and myocardial infarction.

Main Methods:

Utilized 64-slice MDCT to analyze intramyocardial fat in 100 healthy individuals and 25 patients with myocardial infarction.
Defined intramyocardial fat based on Hounsfield unit density (-30 to -190 HU) before and after contrast administration.
Examined fat deposition in 17 LV and 10 RV segments across three ventricular levels.

Main Results:

In healthy individuals, LV fat was mainly in basal segments; RV fat was prominent in anterolateral and inferolateral segments.
Older age correlated with increased RV intramyocardial fat, while men showed a higher risk of LV fat compared to women.
Patients with prior myocardial infarction exhibited increased intramyocardial fat in infarcted LV segments.

Conclusions:

MDCT is effective for detecting intramyocardial fat.
Intramyocardial fat is prevalent in both healthy and infarcted myocardium.
Age, sex, and history of myocardial infarction are significant factors influencing intramyocardial fat deposition.