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The postsynaptic density protein, IQ-ArfGEF/BRAG1, can interact with IRSp53 through its proline-rich sequence

Masashi Sanda1, Akifumi Kamata, Osamu Katsumata

  • 1Department of Anatomy, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara, Kanagawa 228-8555, Japan.

Brain Research
|December 17, 2008
PubMed
Summary

IQ-ArfGEF/BRAG1 interacts with IRSp53 at the postsynaptic density, suggesting a role in synaptic function downstream of NMDA receptors. This interaction involves specific protein domains and occurs in certain neurons.

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