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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
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[Pulmonary embolism: the extent of computerized tomography].

E Huchot1, A Crutu, M Le Hénaff

  • 1Groupe d'étude de la thrombose de Bretagne occidentale, EA 38 78, CHU de la Cavale-Blanche, boulevard Tanguy-Prigent, 29609 Brest cedex, France. eric.huchot@chu-brest.fr

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|December 17, 2008
PubMed
Summary

Multidetector-row spiral computed tomography (MDCT) aids pulmonary embolism diagnosis. Clinical probability and d-dimer tests are crucial, but MDCT may require further investigation in select cases.

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Area of Science:

  • Radiology
  • Cardiology
  • Pulmonary Medicine

Background:

  • Pulmonary embolism (PE) diagnosis involves clinical assessment and imaging.
  • Advancements in multidetector-row spiral computed tomography (MDCT) have improved diagnostic capabilities.
  • Traditional diagnostic methods like venous doppler ultrasound have limitations, especially in elderly patients.

Purpose of the Study:

  • To evaluate the role of MDCT in diagnosing pulmonary embolism.
  • To assess the integration of clinical probability assessment and d-dimer assays with MDCT.
  • To explore complementary diagnostic strategies when MDCT results are inconclusive.

Main Methods:

  • Review of clinical research on computed tomography for PE diagnosis.
  • Assessment of MDCT performance against reference strategies and in pragmatic trials.
  • Evaluation of preliminary clinical probability assessment and d-dimer assays.
  • Consideration of venous doppler ultrasound of the legs.

Main Results:

  • MDCT is a key tool in diagnosing pulmonary embolism.
  • Clinical probability assessment and d-dimer assays are increasingly essential.
  • Venous doppler ultrasound's utility is variable and limited in certain populations.
  • In rare cases, high clinical probability with negative MDCT necessitates further exploration.

Conclusions:

  • MDCT is a valuable diagnostic tool for pulmonary embolism.
  • Integrating clinical assessment and biomarkers improves diagnostic accuracy.
  • Multidisciplinary collaboration between clinicians and radiologists is vital for managing complex cases.